2022 VIRTUAL POSTER HALL

Top 4 Abstract Presenters

#0017

Trends, Predictors and Outcomes of Cardiovascular Complications at Delivery Associated with Gestational Diabetes Mellitus-A National Inpatient Sample Analysis (2004-2019)

#0066

Prognostic value of Triglyceride-Glucose index for the prediction of cardiovascular events: Results from the Multi-Ethnic Study of Atherosclerosis (MESA)

#0027

"OGTT-PLUS" - A Novel Web-App for Model Assessment of Cardio-Vascular Risk in Obesity, Dysmetabolism & Dysglycemia

#0071

NOX5 in Human Peripheral Blood Mononuclear cells: A Promising Biomarker for Unstable Diabetic Vascular Disease

All Accepted Abstracts

Abstracts will be published in the American Heart Journal
Editor-in-Chief: Daniel Mark, MD, MPH

#0002

The Impact of Obesity on Serum Atherogenicity and Cardiovascular Risk

Simona Opriş, Gianina-Ioana Constantin

#0005

Impact of diabetes mellitus on early clinical outcome and stent restenosis after carotid artery stenting

Alexandru Achim MD, Dávid Lackó, Artúr Hüttl MD, Csaba Csobay Novák MD PhD, Ádám Csavajda MD, Péter Sótonyi MD DsC, Béla Merkely MD DsC, Balázs Nemes MD PhD, Zoltán Ruzsa MD PhD
University of Szeged, Medical Faculty, Department of Internal Medicine, Invasive Cardiology Division, Szeged, Hungary Semmelweis University, Cardiac, and Vascular Center, Budapest, Hungary

#0007

Benefits of Fiber-Rich Snack on Waist Circumference and Atergenic Index of Plasma in Obese

Fatma Syukrina, Sunarti, Ika Ratna Palupi

#0012

Efficacy of Liraglutide versus Gliclazide in Treatment of Patients with Type II Diabetes Mellitus: Systematic Review and Meta-Analysis

Manar Ahmed Kamal, Raneem Mahmoud Al-Arawi, Mohamed Ahmed Kamal

#0014

Weight Status and Cardiovascular Diseases in Nely Diagnosed Diabetes

Andreea Morosanu, Magdalena Morosanu

#0015

Association of Plaque Burden with Insulin Resistance represented by Triglyceride -High Density Protein Ratio

Luay Alalawi, April Kinninger, Venkat Sanjay Manubolu, Dhiran Verghese, Ahmed Shafter, Ahmed K. Ghanem, Omar AlTaweel, Khadije Ahmad, Ilana Golub, Zahra Al-chokhachi, George Boll, Orly Termeie, Lucia Schroeder, Stephanie Kristo, Sion Roy, Matthew J. Budoff,

#0019

Coagulation and Cognitive Function - Science Behind the Scenes

Edin Begic, Slobodan Jankovic, Mirsada Causevic

#0021

MiRNAs as Potential Diagnostic Tool for Diabetes-linked Myocardial Infarction

Sana Karim, Ayesha Ishtiaq, Iram Murtaza

#0025

Side Effect Synergism Between Metformin and GLP-1 Receptor Agonists

Cristiano, E and Miles, JM

#0028

Efficacy and Safety of Tirzepatide in Type 2 Diabetes: The SURPASS Clinical Trial Program

Mike Barros, Joshua A. Levine

#0030

Biomarkers in Determining the Risk of Liver Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease and Hypertension

Anastasiia Rozhdestvenska, MD, PhD student, Natalia Zhelezniakova, MD, Doctor of Medicine, Professor

#0032

Potential CYP3A4-Mediated Drug-Drug Interactions with Ritonavir-Containing Medications in U.S. Patients with Diabetes or Cardiovascular Diseases: An Analysis of NHANES Data

Ebuwa Igho-Osagie, Kaylen Brzozowski, Harry Jin, Jeff Brown, Amy Puenpatom

#0034

Relationship Between HbA1c, Non HDLc, Triglyceride/HDL Cholesterol Ratio and Triglyceride Glucose Index in Diabetes Patients

Sushil Baral, Amar Poudel,  Ananta Bhakta Uprety,  Rupesh Kshetri

#0036

Commorbidity Burden in Patients with Covid-19 Treated with Molnupiravir in the United States

Girish Prajapati; Amar Das; Yezhou Sun; Eileen Fonseca

#0038

Change in Galectin-3 (Marker of Fibrosis) during Empagliflozin Therapy.

K. Tchaava, N. Gegeshidze, M. Shavdia, N. Ninashvili, T. Shervashidze

#0040

Association of QT Markers of Arrhythmia and Familial Mediterranean Fever: A Meta-Analysis

Karam R.Motawea, JosephVarney, Omneya A.Kandil, Nancy Ibrahim, Merna Aboelenein1, Bishoy Zaki, Sarya Swed, Mohamed A. Shebl, Zakria Helmy, Ahmed Helmy, Ahmed Khalifa, Mohamed A. Elbahaie, Areeg A. Elbahaie, Arwa A. Elbahaie, Hani Aiash10,11

#0042

Lactate Dehydrogenase can be considered a Predictive Marker of Severity and Mortality of COVID-19 in Diabetic and Non-Diabetic patients. A Case Series

Karam R. Motawea, Joseph Varney, Nesreen E. Talat, Samah S. Rozan, Pensée Chébl, Sarraa M. Reyad

#0044

Periodontal Disease in Association with Myocardial Infarction with Non-Obstructive Coronary Arteries and Microvascular Coronary Artery Disease

Danish Iltaf Satti, Jahanzeb Malik, Syed Muhammad Jawad Zaidi, Farwa Jaffar, Kanwal Latif, Ali Tahir Rana, Mamoona Zahoor, Waheed Akhtar

#0046

Exploring the Role of Micro RNAs as Key Regulators of Diabetic Nephropathy Indiced Cardiovascular Diseases

Javaria Nawaz, Iram Mushtaq, Iram Murtaza.

#0048

Correlation Between Oxidized Low Density Lipoproteins and Metabolic Syndrome in Older Patients

Gianina Ioana Constantin, Simona Opris, Catalina Monica Pena

#0050

Zofenopril Treatment Efficacy on Survival, Endostatin and Insulin-Like Growth Factor-1 in Patients with Diabetes Mellitus Type 2 after Acute Myocardial Infarction

Valeriy Kapustnyk, Borys Shelest, Dmytro Martovytskyi, Yuliia Kovalova

#0052

Effect of Early Metoprolol before PCI in ST-Segment Elevation Myocardial Infarction on Infarct Size and Left Ventricular Ejection Fraction. A Systematic Review and Meta-Analysis

Karam R.Motawea, Hamed Gaber1, Ravi B. Singh, Sarya Swed, Salem Elshenawy, Nesreen Elsayed Talat1, Nawal Elgabrty, Sheikh Shoib, Engy A. Wahsh, Sara Gebril, Mohamed Kishk, Omar A. Elkoumi, Mazen Attia, Ahmed Khalifa, Omar Khaled Habib, Ahmed Foad, Yousef Tanas, Yomna E. Dean, Walaa Hasan, Hani Aiash

#0054

Echocardiography Findings in a Cohort of Older Diabetic Patients with Diastolic Dysfunction: Do they Fall Under the Diabetic Cardiomyopathy Diagnosis?

Adrian Valverde, MD; Richard G. Vaca, MD; Silvia Caceres Vinueza, MD, PhD; Yan Carlos Duarte Vera, MD, PhD

#0056

Relationship Between Vaccines Against Coronavirus Disease 2019 (COVID-19) and Myocarditis

Lorena Araujo Silva Dias, Nathalia Monerat Pinto Blazuti Barreto

#0058

Finerenone in Mild to Severe Chronic Kidney Disease and Type 2 Diabetes: A Fidelity Subgroup Analysis in Patients with Heart Failure

Gerasimos Filippatos, Rajiv Agarwal, Stefan D. Anker, Peter Rossing, Amer Joseph, Peter Kolkhof, Marc Lambelet, Marco A. L. Viaud, Luis M. Ruilope, George L. Bakris, Bertram Pitt, on behalf of the FIDELIO-DKD and FIGARO-DKD investigators

#0060

Clinical data and diagnostic findings in patients with ischemic heart disease undergoing coronary angiography: a cross-sectional study from a tertiary hospital in Sudan, Africa

Elfatih A. Hasabo, Ghassan E. Mustafa, Anab M. Jabir, Mohammed H. Omer, Mohammed A. Abdalla, Wefag Hussein Mohammed, Ahmed A A Suliman, FACP, FESC

#0062

DNA-methylation Signature of MicroRNA Coding Genes Associated with Chronological Age in a High-Cardiovascular Risk Mediterranean Population. Sex-specific Analysis

Rebeca Fernández Carrión, José V. Sorlí Guerola, Eva C. Pascual Castelló, Carolina Ortega-Azorín, Rocío Barragán Arnal, Eva M. Asensio Márquez, Laura Viviana Villamil Penagos, Dolores Corella Piquer, Oscar Coltell Simón

#0064

IL-6 as a Surrogate Biomarker: The IL-6 Clinical Value for the Diagnosis of Insulin Resistance and Type 2 Diabetes

Rafik R, Andrew RR, Mark RR, Alaa I

#0068

Breastfeeding Impact on Kidney Functions : A Systematic Review

N. Boutrid, H. Rahmoune, B. Bioud, D. Abdelmalek, M. Amrane

#0070

Central Venous Access: Conventional Seldinger Versus Ultrasound-Guided Technique to Reduce Associated Complications in a School Hospital

Velasquez Jose, Pinto Jimena

#0073

10-year Follow-up of Neurodegeneration and Concomitant Cardiometabolic Diseases as Risk Factors for Seborrheic dermatitis

Kevin Sheng-Kai Ma, Irene Lee

#0075

Prediction of In-Hospital Mortality among Heart Failure patients: An Automated Machine Learning Analysis of MIMIC-III database

Aliya Ali, Saleha Yurf Asghar, Ali Danish Khan Yousafzai, Ali Haider Bangash*, Rabia Mohsin, Arshiya Fatima, Saiqa Zehra, Ayesha Khalid Khan, Ali Haider Shah, Syed Mohammad Mehmood Abbas, Syed Muhammad Qasim Shah, Hashir Fahim Khawaja, Ain ul Badar, Adil Baloch, Ambar Sattar Khan, Asjad Ullah Khan, Aymen Yunus, Farhan Faisal, Gulfam Jameel, Kashaf Mushtaq, Muhammad Awais Bilal, Maryam Naveed Abbasi, Mehwish Nawaz, Mishal Bilal, Muhammad Ashraf, Musa Kamil, Namira Khan Khakwani, Noor Ayesha, Oneeza Tariq Sadaf Khalid, Shafquat Rasool

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#0077

The Effect of Avocado Drink (Persea Americana Mill) on the Incidence of Ballooning Hepatocyte in the Liver Organs of Rats (Rattus Novergicus) Induced by Hypercholesterolemia

Helga Febrina Kinayahnty, Miranti Dewi Pramaningtyas, Rokhima Lusiantari, Hanggoro Tri Rinonce

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#0087

Bempedoic Acid for Management of Dyslipidemia from an Indian Perspective: An Expert Consensus Report

Srinivasa Rao Maddury1, JPS Sawhney 2, Prafulla G Kerkar 3, Piyush Jain 4, Praveen Chandra 5, T. Sashikant6, Jay Shah 7, Jitendra Singh Makkar8, Bino Benjamin9, Rachel Daniel10, Dharmesh Solanki 11, A B Chandorkar12 B Yugandhar13, Kamal Sharma14 (National study group)

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#0091

Longitudinal Study of New Diabetes Cases at Seven Years in a Risk-Sample of Peruvian Subjects with Elevated 1-Hour OGTT

Juan Carlos Lizarzaburu-Robles, Alonso Garro-Mendiola, Flor Vento

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#0004

End-Stage Renal Disease is Associated with Increased Inpatient Mortality in Patients Admitted for Atrial Fibrillation: Analysis of the National Inpatient Sample

Richard Orji, MD (1, 2); Michael Fatuyi, MD (3); Jashan Gill, MD (1, 2); Adedoyin Olawoye, MD (4); Aman Dutta, MD (1, 2); Komal Malik, MD (1, 2); Kevin Nabhan, Ebehireme Ukpokolo

#0006

Prevalence of Dyslipidaemia, Obesity and Vitamin D Insufficiency among Patients Attending the Diabetic Clinic at Queen Elizabeth Central Hospital in Malawi

Kondwani Katundu, Victoria Mukhula, Johnstone Kumwenda, Mwapatsa Mipando1, Adamson Muula, Tamara Phiri, Chimota Phiri, Fanuel Lampiao1, Henry Mwandumba

#0008

Dyslipidaemia Patterns and Risk Factors among Patients with Diabetes, Hypertension, and both Diabetes and Hypertension at a Tertiary Hospital in Malawi

Kondwani Katundu, Victoria Mukhula, Johnstone Kumwenda, Mwapatsa Mipando, Adamson Muula, Tamara Phiri, Chimota Phiri, Fanuel Lampiao, Henry Mwandumba

#0013

Variation in the RAC1 Gene is Linked to Cardiovascular Autonomic Neuropathy and Distal Neuropathy in Type 2 Diabetes Patients

Iuliia Azarova, Victor Makarenko, Elena Klyosova, Alexey Polonikov

#0016

Prevalence of Kidney and Hepatic Dysfunction, and Outcomes in Hospitalized Patients With COVID-19 Infection in SBA region (west of Algeria)

Demmouche Abbassia*, Abdallah Touati Djihène, Bouazza Sofiane ; Belmous Asmaa

#0018

Estimate Patient's 10-years Cardiovascular Risk using Arteriosclerotic Cardiovascular Disease Tool a Cross-Sectional Study in Al-Harja, Asser, Saudi Arabia,2021.

Abdulrahman Saeed , Abdullah Saeed and Bahaa Abaalkhail

#0020

Investigating the MicroRNAs as Key Regulator in Diabetic Cardiomyopathy

Iqra Azhar, Ayesha Ishtiaq, Iram Murtaza

#0023

Influence of Body Mass Index and Glucose Metabolism on Results of CABG for High Risk Patients.

Olena Gogayeva, Anatolii Rudenko, Vasyl Lazoryshynets

#0026

Predictors of Major Adverse Limb Events After Infrainguinal Bypass in Patients with Diabetes

Dana Alameddine, Keyuree Satam, Martin Slade, He Wang, Carlos Mena-Hurtado, Jeffrey Turner, Silvio E Inzucchi, Cassius Iyad Ochoa Chaar

#0029

Micro RNAs as potential Biomarkers for Early-Stage Diagnosis of Hyperglycemia Induced Cardiac Autoimmunity

Rafia Gul, Iram Mushtaq, Iram Murtaza.

#0031

Telomere, Telomerase and The Aging Heart

Ahmed Saad Elsaeidy, Manar Ahmed Kamal, Mostafa Sameh, Ahmed Fady Fouad 

#0033

Combination of Baicalin and Catechin Effectively Attenuates Doxorubicin-Induced Cardiotoxicity through Modulation of DKK1-Wnt/β-Catenin and TLR4/NF-κB Pathways

Salwa R. Abo El-Ela1, Randa A. Zaghloul1,*, Laila A. Eissa1, *

#0035

Major Adverse Cardiovascular Events Across the Sotagliflozin Clinical Development Program

Michael J. Davies, Franklin Sun, Phillip Banks, Deepak L. Bhatt, Bertram Pitt

#0037

In-Silico Profiling of MiRNAs Against Type 2 Diabetes Mellitus and Myocardial Infarction Associated Genes

Khadam Hussain, Muhammad Yousaf, Iram Murtaza

#0039

Results From a Randomized, Open-Label, Crossover Study Evaluating Pharmacokinetic Interaction Between the Aldosterone Synthase Inhibitor Baxdrostat and Metformin in Healthy Human Subjects

Mason W. Freeman, Mary Bond, Brian Murphy, James Hui, and Jonathan Isaacsohn

#0041

Coronary Embolism after Infection with COVID-19 in Non-Diabetic Non-Hypertensive Patient. A Case Report

Karam R. Motawea, Sarraa M. Reyad1, Pensée Chébl

#0043

Statin Therapy is Associated with Higher Risk of Diabetic Complications: A Population-Based Cohort Study

Danish Iltaf Satti, Teddy Tai Loy Lee, Oscar Hou In Chou, Chengsheng Ju, Evbayekha Endurance Osas, Gary Tse, Sharen Lee

#0045

Intranasal Co-Administration of Insulin and C-Peptide Restores Metabolic and Hormonal Indices in Rats with Normoinsulinemic, bur not with Hyperinsulinemic, Type 2 Diabetes

Stepochkina A.M., Derkach K.V., Bondareva V.M., Bakhtyukov A.A., Shpakov A.O.

#0047

Single Nucleotide Variants of the MCM6 Gene as a Risk Factor for Metabolically Unhealthy Obesity in Children

Aleksandr Abaturov, Anna Nikulina, Dmytro Nikulin

#0049

Relationship Between Vaccines Against Coronavirus Disease 2019 (COVID-19) and Myocarditis

Lorena Araujo Silva Dias, Nathalia Monerat Pinto Blazuti Barreto

#0051

Efficacy of Anterior Lateral Electrode Compared with Anterior Posterior Electrode in External Cardioversion of Atrial Fibrillation. A Meta-Analysis of Clinical Trials

Karam R. Motawea, Mostafa Reda Mostafa, Mohamed Magdi, Sarya Swed, Hager Fathy, Merna Aboelenein, Mohamed Mohamed Belal, Dina M. Awad, Nesreen Elsayed Talat, Samah S. Rozan, Sana Afreen Ansari, Rameen Shahid, Taher Sbitli, Ramy Eweis, Bdoor Bamousa, Muaaz Aslam, Yousef Tanas, Yomna E. Dean, Walaa Hasan, Hani Aiash

#0053

Association of Increased Fructose Comsumption with Atrial Fibrillation Symptoms

Mevlut Serdar Kuyumcu, Aliye Kuyumcu, Sebahat Ulusan

#0055

Selenium Metabolism and Systemic Inflammation in Hypertensive Patients with Nonalcoholic Fatty Liver Disease

Iryna Tverezovska, Natalia Zhelezniakova

#0057

Finerenone and Cardiorenal Outcomes by History of Cardiovascular Disease in Patients with Type 2 Diabetes: Fidelity Analyses

Gerasimos Filippatos, Stefan D. Anker, Bertram Pitt, Peter Rossing, Luis M. Ruilope, Darren K. McGuire, Ewa A. Jankowska, Erin D. Michos, Javed Butler, Alfredo E. Farjat, Peter Kolkhof, Andrea Scalise, Amer Joseph, Marco A. L. Viaud, George L. Bakris, Rajiv Agarwal, on behalf of the FIDELIO-DKD and FIGARO-DKD Investigators

#0059

Prevalence of Infection and Effect of Diabetes on Clinical Presentations of Patients Diagnosed with Ischemic Heart Disease Admitted to Coronary Angiography

Elfatih A. Hasabo, Ghassan E. Mustafa, Alaa S. Ahmed, Walaa Elnaiem, Ahmed A A Suliman, FACP, FESC

#0061

Clinical characteristics and treatment of patients with ischemic heart disease underwent percutaneous coronary intervention (PCI): an African experience from a tertiary hospital

Elfatih A. Hasabo, Ghassan E. Mustafa, Anab M. Jabir, Mohammed H. Omer, Mohammed A. Abdalla, Wefag Hussein Mohammed, Ahmed A A Suliman, FACP, FESC

#0063

Self-Medication Practices from the Perspective of Tunisian Cardiovascular Patients – A Community Pharmacy-Based Survey

Maria Suciu, Lavinia Vlaia, Eya Boujneh, Liana Suciu, Valentina Oana Buda, Vicențiu Vlaia, Carmen Cristescu

#0065

Kidney Dysfunction in Central Obesity Associated Metabolic Disorders

Katalin Csép*, Ágnes Bálint**

#0069

Risk Factors and Evidence Based Interventions for Cardiometabolic Disease in the South Asian Diaspora

Pranav Mellacheruvu BS*, Suhaas Bonkur, Neha J Pagidipati, MD, MPH

#0072

Heart Failure, Sepsis, and All-Cause Mortality Following Seborrheic Dermatitis: A Multi-Center Cohort Study

Kevin Sheng-Kai Ma, Irene Lee

#0074

Incorporating Ensembled stacked approach into Automated Machine Learning in an attempt to predict acute ischemic heart disease in patients with atypical chest pain: Secondary analysis of a single-center retrospective cohort study

Hashir Fahim Khawaja, Aliya Ali, Saleha Yurf Asghar, Rabia Mohsin, Ali Danish Khan Yousafzai, Ali Haider Bangash*, Arshiya Fatima, Saiqa Zehra, Ali Haider Shah, Syed Mohammad Mehmood Abbas, Syed Muhammad Qasim Shah, Ain ul Badar, Adil Baloch, Ambar Sattar Khan, Asjad Ullah Khan, Ayesha Khalid Khan, Aymen Yunus, Farhan Faisal, Gulfam Jameel, Kashaf Mushtaq, Muhammad Awais Bilal, Maryam Naveed Abbasi, Mehwish Nawaz, Mishal Bilal, Muhammad Ashraf, Musa Kamil, Noor Ayesha, Oneeza Tariq, Sadaf Khalid, Shafquat Rasool

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#0076

Gold nanoparticles: A potential Therapeutic Target for Diabetic Nephropathy through Regulation of miR-192, miR-21, autophagy, apoptosis and fibrosis

Samar. M. Al-Tantawy*, Salma. M. Eraky , Laila. A. Eissa*

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#0081

Q-wave Myocardial Infarction & Stroke in Patients Managed Interventionally for Left Main Coronary Artery Disease: Prediction by Incorporation of Ensemble approach into Automated Machine Learning

Ali Danish Khan Yousafzai(1)§, Saleha Yurf Asghar(1)§, Hashir Fahim Khawaja(1)§, Syed Mohammad Mehmood Abbas(1)§, Ali Haider Bangash(1)§*, Ain ul Badar¶, Adil Baloch(1)¶, Ali Haider Shah(1)¶, Aliya Ali(1)¶, Ambar Sattar Khan(1)¶, Arshiya Fatima(1)¶, Ayesha Khalid Khan(1)¶, Asjad Ullah Khan(1)¶, Aymen Yunus(1)¶, Farhan Faisal(1)¶, Gulfam Jameel(1)¶, Kashaf Mushtaq(1)¶, Muhammad Awais Bilal(1)¶, Maryam Naveed Abbasi(1)¶, Mehwish Nawaz(1)¶, Mishal Bilal(1)¶, Muhammad Ashraf(2)¶, Musa Kamil(1)¶, Namira Khan Khakwani(1)¶, Noor Ayesha(1)¶, Oneeza Tariq(1)¶, Osama Ahmed(1)¶, Rabia Mohsin(1)¶, Sadaf Khalid(1)¶, Saiqa Zehra(1)¶, Shafquat Rasool(1)¶, Syed Muhammad Qasim Shah(1)¶ § These authors contributed equally to data curation, development of methodology, statistical analyses and writing with subsequent reviewing and editing of the abstract draft. ¶ These authors, indicated alphabetically, contributed equally to statistical analyses and validation.

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#0082

Yurf-Bangash-Yousafzai augur : Proposal of Carotid Plaque Formation predictor among general population by Exploration of State-of-the-Art for Automated Machine Learning

Saleha Yurf Asghar(1)§, Ali Haider Bangash(1)§*, Ali Danish Khan Yousafzai(1)§, Syed Mohammad Mehmood Abbas(1)§, Hashir Fahim Khawaja(1)§, Ain ul Badar¶, Adil Baloch(1)¶, Ali Haider Shah(1)¶, Aliya Ali(1)¶, Ambar Sattar Khan(1)¶, Arshiya Fatima(1)¶, Ayesha Khalid Khan(1)¶, Asjad Ullah Khan(1)¶, Aymen Yunus(1)¶, Farhan Faisal(1)¶, Gulfam Jameel(1)¶, Kashaf Mushtaq(1)¶, Muhammad Awais Bilal(1)¶, Maryam Naveed Abbasi(1)¶, Mehwish Nawaz(1)¶, Mishal Bilal(1)¶, Muhammad Ashraf(2)¶, Musa Kamil(1)¶, Namira Khan Khakwani(1)¶, Noor Ayesha(1)¶, Oneeza Tariq(1)¶, Osama Ahmed(1)¶, Rabia Mohsin(1)¶, Sadaf Khalid(1)¶, Saiqa Zehra(1)¶, Shafquat Rasool(1)¶, Syed Muhammad Qasim Shah(1)¶ § These authors contributed equally to data curation, development of methodology, statistical analyses and writing with subsequent reviewing and editing of the abstract draft. ¶ These authors, indicated alphabetically, contributed equally to statistical analyses and validation.

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